Through genomic research, we continue to learn more about the complexity of cancer. While cancer continues to be identified by its location in the body (lung, breast, blood, etc.), we have learned that a more accurate way to evaluate cancer treatment is through examination of the underlying changes or mutations which drive cancer development and progression. Those mutations are not limited to location and, in many instances, have very little correlation with the location. Understanding the core genetic mutations which drive cancer progression allows clinicians to replace more traditional treatments with newer, less toxic, therapies that target those specific mutations.